PrimePCR™ ddPCR™ Expression Probe Assay: RPS19, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0032592; Exonic

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5028970
Chromosome Location:   19:42363994-42364125question
Amplicon Length:   102

Gene Information

Ribosomes the organelles that catalyze protein synthesis consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S19E family of ribosomal proteins. It is located in the cytoplasm. Mutations in this gene cause Diamond-Blackfan anemia (DBA) a constitutional erythroblastopenia characterized by absent or decreased erythroid precursors in a subset of patients. This suggests a possible extra-ribosomal function for this gene in erythropoietic differentiation and proliferation in addition to its ribosomal function. Higher expression levels of this gene in some primary colon carcinomas compared to matched normal colon tissues has been observed. As is typical for genes encoding ribosomal proteins there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq Jul 2008]

Gene Symbol:   RPS19
Gene Name:   ribosomal protein S19
Aliases:   DBA, DBA1, S19
RefSeq:   NC_000019.9 NG_007080.2 NT_011109.16
Ensembl:   ENSG00000105372
Entrez:   6223
UniGene:   Hs.438429
Chromosome Mapping:   19q13.2

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