PrimePCR™ ddPCR™ Expression Probe Assay: SUMO4, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0032415; Exonic

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5028762
Chromosome Location:   6:149721704-149721806question
Amplicon Length:   73

Gene Information

This gene is a member of the SUMO gene family. This family of genes encode small ubiquitin-related modifiers that are attached to proteins and control the target proteins' subcellular localization stability or activity. The protein described in this record is located in the cytoplasm and specifically modifies IKBA leading to negative regulation of NF-kappa-B-dependent transcription of the IL12B gene. A specific polymorphism in this SUMO gene which leads to the M55V substitution has been associated with type I diabetes. The RefSeq contains this polymorphism. [provided by RefSeq Jul 2008]

Gene Symbol:   SUMO4
Gene Name:   SMT3 suppressor of mif two 3 homolog 4 (S. cerevisiae)
Aliases:   IDDM5, SMT3H4, SUMO-4, dJ281H8.4
RefSeq:   NC_000006.11 NG_012301.1 NG_021386.1 NT_025741.15
Ensembl:   ENSG00000177688
Entrez:   387082
UniGene:   Hs.657168
Chromosome Mapping:   6q25

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