PrimePCR™ ddPCR™ Expression Probe Assay: PSMB11, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0032081; Exonic

Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5028284
Chromosome Location:   14:23512521-23512611question
Amplicon Length:   61

Gene Information

Proteasomes generate peptides that are presented by major histocompatibility complex (MHC) I molecules to other cells of the immune system. Proteolysis is conducted by 20S proteasomes complexes of 28 subunits arranged as a cylinder in 4 heteroheptameric rings: alpha-1 to -7 beta-1 to -7 beta-1 to -7 and alpha-1 to -7. The catalytic subunits are beta-1 (PSMB6; MIM 600307) beta-2 (PSMB7; MIM 604030) and beta-5 (PSMB5; MIM 600306). Three additional subunits beta-1i (PSMB9; MIM 177045) beta-2i (PSMB10; MIM 176847) and beta-5i (PSMB8; MIM 177046) are induced by gamma-interferon (IFNG; MIM 147570) and are preferentially incorporated into proteasomes to make immunoproteasomes. PSMB11 or beta-5t is a catalytic subunit expressed exclusively in cortical thymic epithelial cells (Murata et al. 2007 [PubMed 17540904]).[supplied by OMIM Mar 2008]

Gene Symbol:   PSMB11
Gene Name:   proteasome (prosome, macropain) subunit, beta type, 11
Aliases:   BETA5T, FLJ16369
RefSeq:   NC_000014.8 NT_026437.12
Ensembl:   ENSG00000222028
Entrez:   122706
UniGene:   Hs.508918
Chromosome Mapping:   14q11.2

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