PrimePCR™ ddPCR™ Expression Probe Assay: HYAL2, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0025899; Exonic

 
Fluorophore:   FAM
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5028108
Chromosome Location:   3:50355675-50355837question
Amplicon Length:   133

Gene Information

This gene encodes a weak acid-active hyaluronidase. The encoded protein is similar in structure to other more active hyaluronidases. Hyaluronidases degrade hyaluronan one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan and fragments of hyaluronan are thought to be involved in cell proliferation migration and differentiation. Although it was previously thought to be a lysosomal hyaluronidase that is active at a pH below 4 the encoded protein is likely a GPI-anchored cell surface protein. This hyaluronidase serves as a receptor for the oncogenic virus Jaagsiekte sheep retrovirus. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. This gene encodes two alternatively spliced transcript variants which differ only in the 5' UTR.[provided by RefSeq Mar 2010]

Gene Symbol:   HYAL2
Gene Name:   hyaluronoglucosaminidase 2
Aliases:   LUCA2
RefSeq:   NC_000003.11 NT_022517.18
Ensembl:   ENSG00000068001
Entrez:   8692
UniGene:   Hs.76873
Chromosome Mapping:   3p21.3

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