PrimePCR™ ddPCR™ Expression Probe Assay: COX11, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0025887; Exonic

 
Fluorophore:   HEX
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5028085
Chromosome Location:   17:53045876-53046004question
Amplicon Length:   99

Gene Information

Cytochrome c oxidase (COX) the terminal component of the mitochondrial respiratory chain catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit but may be a heme A biosynthetic enzyme involved in COX formation according to the yeast mutant studies. However the studies in Rhodobacter sphaeroides suggest that this gene is not required for heme A biosynthesis but required for stable formation of the Cu(B) and magnesium centers of COX. This human protein is predicted to contain a transmembrane domain localized in the mitochondrial inner membrane. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene has been found on chromosome 6. [provided by RefSeq Jun 2009]

Gene Symbol:   COX11
Gene Name:   COX11 cytochrome c oxidase assembly homolog (yeast)
Aliases:   COX11P
RefSeq:   NC_000017.10 NT_010783.15
Ensembl:   ENSG00000166260
Entrez:   1353
UniGene:   Hs.591171
Chromosome Mapping:   17q22

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