PrimePCR™ ddPCR™ Expression Probe Assay: SELPLG, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0025880; Exonic

 
Fluorophore:   FAM
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5028070
Chromosome Location:   12:109017822-109017981question
Amplicon Length:   130

Gene Information

This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P- E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.[provided by RefSeq Apr 2011]

Gene Symbol:   SELPLG
Gene Name:   selectin P ligand
Aliases:   CD162, CLA, PSGL-1, PSGL1
RefSeq:   NC_000012.11 NT_029419.12
Ensembl:   ENSG00000110876
Entrez:   6404
UniGene:   Hs.591014
Chromosome Mapping:   12q24

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