This is the amplicon context sequence in accordance with the minimum information for the publication of real-time quantitative PCR experiements (MIQE) guidelines. For more details, please refer to the following publication, "Primer Sequence Disclosure: A Clarification of the MIQE Guidelines."
ddPCR™ probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.
Info: HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0025835; Exonic
Relaxins are known endocrine and autocrine/paracrine hormones belonging to the insulin gene superfamily. In the human there are three non-allelic relaxin genes RLN1 RLN2 and RLN3. RLN1 and RLN2 share high sequence homology. The active form of the encoded protein consists of an A chain and a B chain but their cleavage sites are not definitely described yet. Relaxin is produced by the ovary and targets the mammalian reproductive system to ripen the cervix elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility regulating blood pressure controlling heart rate and releasing oxytocin and vasopressin. There are two alternatively spliced transcript variants encoding different isoforms described for this gene. [provided by RefSeq Jul 2008]