PrimePCR™ ddPCR™ Expression Probe Assay: IL2RB, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0025447; Exonic

 
Fluorophore:   HEX
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5027499
Chromosome Location:   22:37522177-37522366question
Amplicon Length:   160

Gene Information

The interleukin 2 receptor which is involved in T cell-mediated immune responses is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein. [provided by RefSeq Jul 2008]

Gene Symbol:   IL2RB
Gene Name:   interleukin 2 receptor, beta
Aliases:   CD122, IL15RB, P70-75
RefSeq:   NC_000022.10 NT_011520.12
Ensembl:   ENSG00000100385
Entrez:   3560
UniGene:   Hs.474787
Chromosome Mapping:   22q13,22q13.1

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