PrimePCR™ ddPCR™ Expression Probe Assay: SH3BP2, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0025338; Exonic

Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5027403
Chromosome Location:   4:2840420-2840559question
Amplicon Length:   110

Gene Information

The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain an SH3-binding proline-rich region and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T natural killer (NK) and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Mar 2009]

Gene Symbol:   SH3BP2
Gene Name:   SH3-domain binding protein 2
Aliases:   3BP-2, 3BP2, CRBM, CRPM, FLJ42079, FLJ54978
RefSeq:   NC_000004.11 NG_011609.1 NG_012037.1 NT_006051.18
Ensembl:   ENSG00000087266
Entrez:   6452
UniGene:   Hs.167679
Chromosome Mapping:   4p16.3

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