PrimePCR™ ddPCR™ Expression Probe Assay: PCDHGA11, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0025294; Exonic

 
Fluorophore:   HEX
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5027359
Chromosome Location:   5:140802249-140802390question
Amplicon Length:   112

Gene Information

This gene is a member of the protocadherin gamma gene cluster one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes subfamily B contains 7 genes and 2 pseudogenes and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large variable region exons are followed by a constant region containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq Jul 2008]

Gene Symbol:   PCDHGA11
Gene Name:   protocadherin gamma subfamily A, 11
Aliases:   PCDH-GAMMA-A11
RefSeq:   NC_000005.9 NG_000012.2 NT_029289.11
Ensembl:   ENSG00000253873
Entrez:   56105
UniGene:   Not Available
Chromosome Mapping:   5q31

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