PrimePCR™ ddPCR™ Expression Probe Assay: BCL2L11, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0025251; Exonic

 
Fluorophore:   HEX
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5027309
Chromosome Location:   2:111881316-111881453question
Amplicon Length:   108

Gene Information

The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family including BCL2 BCL2L1/BCL-X(L) and MCL1 and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF) as well as by the forkhead transcription factor FKHR-L1 which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq Jul 2008]

Gene Symbol:   BCL2L11
Gene Name:   BCL2-like 11 (apoptosis facilitator)
Aliases:   BAM, BIM, BIM-alpha6, BIM-beta6, BIM-beta7, BOD, BimEL, BimL
RefSeq:   NC_000002.11 NT_022135.16
Ensembl:   ENSG00000153094
Entrez:   10018
UniGene:   Hs.469658
Chromosome Mapping:   2q13

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