This is the amplicon context sequence in accordance with the minimum information for the publication of real-time quantitative PCR experiements (MIQE) guidelines. For more details, please refer to the following publication, "Primer Sequence Disclosure: A Clarification of the MIQE Guidelines."
ddPCR™ probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.
Info: HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0025211; Exonic
The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR a receptor with seven transmembrane domains can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation maturation and presentation of the CGRP receptor to the cell surface. [provided by RefSeq Jul 2008]