PrimePCR™ ddPCR™ Expression Probe Assay: SUN2, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0025190; Exonic

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5027232
Chromosome Location:   22:39146233-39146915question
Amplicon Length:   75

Gene Information

SUN1 (MIM 607723) and SUN2 are inner nuclear membrane (INM) proteins that play a major role in nuclear-cytoplasmic connection by formation of a 'bridge' across the nuclear envelope known as the LINC complex via interaction with the conserved luminal KASH domain of nesprins (e.g. SYNE1; MIM 608441) located in the outer nuclear membrane (ONM). The LINC complex provides a direct connection between the nuclear lamina and the cytoskeleton which contributes to nuclear positioning and cellular rigidity (summary by Haque et al. 2010 [PubMed 19933576]).[supplied by OMIM Nov 2010]

Gene Symbol:   SUN2
Gene Name:   Sad1 and UNC84 domain containing 2
Aliases:   KIAA0668, MGC133055, MGC133056, UNC84B
RefSeq:   NC_000022.10 NT_011520.12
Ensembl:   ENSG00000100242
Entrez:   25777
UniGene:   Hs.517622
Chromosome Mapping:   22q13.1

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