PrimePCR™ ddPCR™ Expression Probe Assay: EIF4G1, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0024464; Exonic

 
Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5026169
Chromosome Location:   3:184040643-184040891question
Amplicon Length:   90

Gene Information

The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants some of which are derived from alternative promoter usage. [provided by RefSeq Aug 2010]

Gene Symbol:   EIF4G1
Gene Name:   eukaryotic translation initiation factor 4 gamma, 1
Aliases:   DKFZp686A1451, EIF-4G1, EIF4F, EIF4G, EIF4GI, P220
RefSeq:   NC_000003.11 NT_005612.16 NG_016850.1
Ensembl:   ENSG00000114867
Entrez:   1981
UniGene:   Hs.433750
Chromosome Mapping:   3q27-qter

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