PrimePCR™ ddPCR™ Expression Probe Assay: RASSF1, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0024147; Exonic

 
Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5025694
Chromosome Location:   3:50367507-50367638question
Amplicon Length:   102

Gene Information

This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1 and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq May 2011]

Gene Symbol:   RASSF1
Gene Name:   Ras association (RalGDS/AF-6) domain family member 1
Aliases:   123F2, NORE2A, RASSF1A, RDA32, REH3P21
RefSeq:   NC_000003.11 NT_022517.18 NG_023270.1
Ensembl:   ENSG00000068028
Entrez:   11186
UniGene:   Hs.476270
Chromosome Mapping:   3p21.3

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