PrimePCR™ ddPCR™ Copy Number Assay: VEGFC, Human

PrimePCR

ddPCR probe assay designed for copy number variation analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; 69nt amplicon; exonic; HEX version of VEGFC (dHsaCP2500485)

 
Fluorophore:   HEX
List Price:    $254.00
Your Price:   Log In
 

Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Copy Number Variation
Unique Assay ID:   dHsaCP2506665
Chromosome Location:   hg194:177605071-177605193question
Amplicon Length:   69
Reference Assays:   , , ,
Restriction Enzymes:   HaeIII

Gene Information

The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family is active in angiogenesis and endothelial cell growth and can also affect the permeability of blood vessels. This secreted protein undergoes a complex proteolytic maturation generating multiple processed forms which bind and activate VEGFR-3 receptors. Only the fully processed form can bind and activate VEGFR-2 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor D. [provided by RefSeq Jul 2008]

Gene Symbol:   VEGFC
Gene Name:   vascular endothelial growth factor C
Aliases:   Flt4-L, VRP
RefSeq:   NC_000004.11 NT_016354.19
Ensembl:   ENSG00000150630
Entrez:   7424
UniGene:   Hs.435215
Chromosome Mapping:   4q34.3

  Download Validation Data (.pdf)


Products used to generate validation data:

ddPCR Instrument QX200
ddPCR Supermix ddPCR Supermix for Probes (no dUTP)
Experimental Sample NA18916,AG09394

Copy Number
Copy number analysis of two samples, using the EIF2C1 reference assay. Technical replicates are shown.

Copy Number Text

ddPCR Amplitude Scatter Plot
Single-well data of target assay (FAM, Channel 1) duplexed to EIF2C1 reference assay (HEX, Channel 2).

ddPCR Amplitude Scatter Plot Text

Number Description Download