PrimePCR™ ddPCR™ Copy Number Assay: DLGAP2, Human

PrimePCR

ddPCR probe assay designed for copy number variation analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; 69nt amplicon; exonic; HEX version of DLGAP2 (dHsaCP1000573)

 
Fluorophore:   HEX
List Price:    $254.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Copy Number Variation
Unique Assay ID:   dHsaCP2506428
Chromosome Location:   hg198:1581075-1581197question
Amplicon Length:   69
Reference Assays:   , , ,
Restriction Enzymes:   HaeIII

Gene Information

The product of this gene is one of the membrane-associated guanylate kinases localized at postsynaptic density in neuronal cells. These kinases are a family of signaling molecules expressed at various submembrane domains and contain the PDZ SH3 and the guanylate kinase domains. This protein may play a role in the molecular organization of synapses and in neuronal cell signaling. Alternatively spliced transcript variants encoding different isoforms have been identified but their full-length nature is not known. This gene is biallelically expressed in the brain however only the paternal allele is expressed in the testis (PMID:18055845). [provided by RefSeq Oct 2010]

Gene Symbol:   DLGAP2
Gene Name:   discs, large (Drosophila) homolog-associated protein 2
Aliases:   DAP2, SAPAP2
RefSeq:   NC_000008.10 NG_009409.1 NT_023736.17
Ensembl:   ENSG00000198010
Entrez:   9228
UniGene:   Hs.113287
Chromosome Mapping:   8p23

  Download Validation Data (.pdf)


Products used to generate validation data:

ddPCR Instrument QX200
ddPCR Supermix ddPCR Supermix for Probes (no dUTP)
Experimental Sample NA18916,AG09394

Copy Number
Copy number analysis of two samples, using the EIF2C1 reference assay. Technical replicates are shown.

Copy Number Text

ddPCR Amplitude Scatter Plot
Single-well data of target assay (FAM, Channel 1) duplexed to EIF2C1 reference assay (HEX, Channel 2).

ddPCR Amplitude Scatter Plot Text

Number Description Download