Illumina and Bio-Rad Launch Solution for Single-Cell Genomic Sequencing to Enable Robust Study of Complex Diseases

Print

Date: 01/09/17

SAN DIEGO and HERCULES, Calif. — January 9, 2017 — Illumina, Inc. (NASDAQ: ILMN) and Bio‑Rad Laboratories, Inc. (NYSE: BIO)(NYSE: BIOb) today announced the launch of the Illumina® Bio-Rad® Single-Cell Sequencing Solution at the J.P. Morgan Healthcare Conference, San Francisco. The comprehensive solution is the first next-generation sequencing (NGS) workflow for single-cell analysis, providing researchers the ability to investigate the coordinated contribution of individual cells in tissue function, disease progression, and therapeutic response.

Single-cell analysis enables a deep view into the gene expression of individual cells to understand their functions in complex tissues. The solution delivers high-throughput sequencing of thousands of individual cells, traditionally a challenging, costly, and time consuming process. Human development and disease research, fields in which single-cell sequencing is widely applicable, is expected to benefit most from this new offering.

“Single-cell genomics provides the opportunity to look at stem cells turning into neurons that are lost in diseases like Parkinson’s and amyotrophic lateral sclerosis (also known as Lou Gehrig's disease) with much higher accuracy,” said Clive Svendsen, PhD, Director, Cedars-Sinai Board of Governors Regenerative Medicine Institute in Los Angeles. His laboratory tested the application of the new platform to profile single cells used in modeling neurodegenerative diseases.

“Using the solution made it possible to detect single cells in a population that was maturing faster than others, allowing us to produce better models of disease,” added Ritchie Ho, PhD, Project Scientist in the Cedars-Sinai Board of Governors Regenerative Medicine Institute and lead researcher for the testing.

The solution comprises the ddSEQ™ Single-Cell Isolator and SureCell™ WTA 3' Library Prep Kit. Bio-Rad’s best-in-class droplet partitioning technology, Droplet Digital™ technology, is used to isolate and barcode single cells for downstream sequencing on many of Illumina’s leading NGS instruments. The comprehensive workflow solution includes primary and secondary data analysis conducted via the BaseSpace® Informatics Suite, Illumina’s cloud-based genomics computing environment, and tertiary data analysis and visualization with SeqGeq™ from FlowJo, LLC, the market leader in flow cytometry analysis.

“Through our close collaboration with Illumina we developed a seamless and scalable solution for single-cell analysis,” said Annette Tumolo, Bio-Rad Executive Vice President and General Manager, Digital Biology Group. “We are proud to equip cell biologists and others in the research community with the tools they need to power new discovery.”

“By offering cell biologists access to technologies that make single-cell analysis cost effective and easy to adopt, we hope to enable scientists to advance complex disease research using gene expression insights,” said Rob Brainin, Vice President and General Manager, Applied Genomics at Illumina. “Our collaboration with Bio-Rad has allowed us to bring this technology to market quickly and empower our customers to unlock the power of the genome to improve human health.” The Illumina® Bio-Rad® Single-Cell Sequencing Solution will begin shipping in early February. For more information about the instruments, reagents, and workflow, visit www.bio-rad.com/ddSEQ.

About Illumina
Illumina is improving human health by unlocking the power of the genome. Our focus on innovation has established us as the global leader in DNA sequencing and array-based technologies, serving customers in the research, clinical and applied markets. Our products are used for applications in the life sciences, oncology, reproductive health, agriculture, and other emerging segments. To learn more, visit www.illumina.com and follow @illumina.

About Bio-Rad
Bio-Rad Laboratories, Inc. (NYSE: BIO) (BIOb) develops, manufactures, and markets a broad range of innovative products and solutions for the life science research and clinical diagnostic markets. The company is renowned for its commitment to quality and customer service among university and research institutions, hospitals, public health and commercial laboratories, as well as the biotechnology, pharmaceutical, and food safety industries. Founded in 1952, Bio-Rad is based in Hercules, California, and serves more than 100,000 research and healthcare industry customers through its global network of operations. The company employs more than 8,000 people worldwide and had revenues exceeding $2 billion in 2015. For more information, please visit www.bio-rad.com.

Illumina Forward-Looking Statements
This release contains forward-looking statements that involve risks and uncertainties, such as Illumina’s expectations regarding the launch of any products. Important factors that could cause actual results to differ materially from those in forward-looking statements include the application of generally accepted accounting principles, which are highly complex and involve many subjective assumptions, estimates, and judgments, and the other factors detailed in Illumina’s filings with the Securities and Exchange Commission, including its most recent filings on Forms 10-K and 10-Q, or in information disclosed in public conference calls, the date and time of which are released beforehand. Illumina assumes no obligation to update any forward-looking statements after the date of this release.

Bio-Rad Forward-Looking Statements
This release may be deemed to contain certain forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. These forward-looking statements include, without limitation, statements we make regarding plans to introduce new products and the opportunities that may result from such new products. Forward-looking statements generally can be identified by the use of forward-looking terminology such as “plan”, “believe,” “expect,” “anticipate,” “may,” “will,” “intend,” “estimate,” “continue,” or similar expressions or the negative of those terms or expressions, although not all forward-looking statements contain these words. Such statements involve risks and uncertainties, which could cause actual results to vary materially from those expressed in or indicated by the forward-looking statements. These risks and uncertainties include our ability to develop and market new or improved products, our ability to compete effectively, international legal and regulatory risks, and product quality and liability issues. For further information regarding our risks and uncertainties, please refer to the “Risk Factors” and “Management’s Discussion and Analysis of Financial Condition and Results of Operation” in Bio-Rad’s public reports filed with the Securities and Exchange Commission, including our most recent Annual Report on Form 10-K and our Quarterly Reports on Form 10-Q. Bio-Rad cautions you not to place undue reliance on forward-looking statements, which reflect an analysis only and speak only as of the date hereof. We disclaim any obligation to update these forward-looking statements.

Press Contacts:
Bio-Rad Laboratories, Inc.
Tina Cuccia, Corporate Communications
510-724-7000
tina_cuccia@bio-rad.com

llumina, Inc.
Investors:
Rebecca Chambers
858-255-5243
rchambers@illumina.com

(or)

Media:
Gwen Gordon
858-882-6822
pr@illumina.com

Sign Up for Bio-Rad Updates!
Enter your email address below to receive your choice of the latest news, promotions, and more.
Illumina-and-Bio-Rad_1484001101 [x-forwarded-proto] = [http] [x-forwarded-port] = [80] [x-forwarded-for] = [52.91.245.237, 10.232.18.243] [accept] = [text/html,application/xhtml+xml,application/xml;q=0.9,*/*;q=0.8] [if-modified-since] = [Tue, 25 Sep 2018 04:00:30 GMT] [seourl] = [/en-us/corporate/newsroom/illumina-bio-rad-launch-solution-for-single-cell-genomic-sequencing-enable-robust-study-complex-diseases] [x-amzn-trace-id] = [Root=1-5c1717f3-d668c304482510faf4d0dca2] [x-forwarded-server] = [lsds-prod-s.br.aws-livesite.io] [x-forwarded-host] = [www.bio-rad.com] [x-query-string] = [ID=Illumina-and-Bio-Rad_1484001101] [host] = [10.232.17.28:1776] [x-request-uri] = [/en-us/corporate/newsroom/illumina-bio-rad-launch-solution-for-single-cell-genomic-sequencing-enable-robust-study-complex-diseases] [connection] = [Keep-Alive] [accept-encoding] = [gzip] [user-agent] = [CCBot/2.0 (https://commoncrawl.org/faq/)] Corporate/CorpNewsDetail pageStyleKey corporate/newsroom/illumina-bio-rad-launch-solution-for-single-cell-genomic-sequencing-enable-robust-study-complex-diseases GNL 03/26/14 02:17 PM en_US true internet/generic 2018-10-10 22:22:20 /default/main/bio-rad/STAGING 1385504243813 US templatedata/internet/generic/data/en_US/GNL/page_generic_footer_b2c_1385505294_US.xml page_generic_footer_b2c /default/main/bio-rad/WORKAREA/default jc7v8okm 2017-10-27 13:13:40 true Done jc7v8okm templatedata/internet/generic/data/en_US/GNL/page_generic_footer_b2c_1385505294_US.xml GNL N /default/main/bio-rad en_US 11/27/23 02:18 PM 1532127468176 2018-10-10 22:22:20 /default/main/bio-rad/WORKAREA/default/templatedata/internet/generic/data/en_US/GNL/page_generic_footer_b2c_1385505294_US.xml footer-page 1 1385504243813 page_generic_footer_b2c <div class="links"> <h4>Support</h4> <ul> <li><a class="msdsLink wtclass linkgeneration" href="/_locale/literature-library">MSDS</a></li> <li><a class="cofaLink wtclass linkgeneration" href="/_locale/_defaultVerticalUrl/support/certificate-of-analysis">Certificate of Analysis</a></li> <li><a class="qcinsertsLink wtclass" href="http://myeinserts.qcnet.com/" target="_blank" rel="noopener noreferrer">QC Inserts</a></li> <li><a class="technicalsupportLink wtclass linkgeneration" href="/_locale/life-science-research/support">Technical Support<br />For Life Science</a></li> <li><a class="expertCSLink wtclass linkgeneration" href="/_locale/_defaultVerticalUrl/purchase-service-programs/expert-care-service?ID=1383780912356">Expert Care Service</a></li> <li><a class="feedBackLink wtclass linkgeneration" id="feedbackID" href="javascript:void(0)">Feedback</a></li> <li><a class="contactUSLink wtclass linkgeneration" href="/_locale/contact-us">Contact Us</a></li> </ul> </div> <div class="links"> <h4>Ordering</h4> <ul> <li><a id="quickOrderLink" class="quickOrderLink wtclass" name="quickOrderLink" href="javascript:openAjaxOverlay('/evportal/portlets/ordering/quickOrderOverlayContent.jsp?quickorder_location=Footer')">Quick Order</a></li> <li><a class="mybioradLink wtclass linkgeneration" href="/_locale/my-bio-rad">My Bio-Rad</a></li> <li><a id="footer_orderLink" class="orderhistoryLink wtclass" href="javascript:void(0);">Order History</a></li> <li><a id="footer_quoteLink" href="javascript:void(0);">Quote History</a></li> <li><a class="supplycentersLink wtclass linkgeneration" href="/_locale/_defaultVerticalUrl/purchase-service-programs/supply-center-program">Supply Centers</a></li> <li><a class="returnpolicyLink wtclass linkgeneration" href="javascript:openAjaxOverlay('/webroot/web/html/returnPolicy-us.html','Return and Refund Policy');">Return and Refund Policy</a></li> </ul> </div> <div class="links"> <h4>Our Products</h4> <ul> <li><a class="lsrLink wtclass linkgeneration" href="/_locale/life-science-research">Life Science Research</a></li> <li><a class="cdLink wtclass linkgeneration" href="/_locale/clinical-diagnostics">Clinical Diagnostics</a></li> <li><a class="infLink wtclass linkgeneration" href="/_locale/spectroscopy">Spectroscopy</a></li> <li><a class="psLink wtclass linkgeneration" href="/_locale/process-separations">Process Separations</a></li> <li><a class="fsLink wtclass linkgeneration" href="/_locale/food-science">Food Science</a></li> <li><a class="lseLink wtclass linkgeneration" href="/_locale/education">Life Science Education</a></li> <li><a class="selectionguideLink wtclass linkgeneration" href="/featured/en/selection-guides.html">Selection Guides</a></li> <li><a class="featuredproductsLink wtclass" href="/featured/en/featured-products.html">Featured Products</a></li> </ul> </div> <div class="links links2"> <h4>Corporate</h4> <ul> <li><a class="aboutbioradLink wtclass linkgeneration" href="/_locale/corporate/about-bio-rad">About Bio-Rad</a></li> <li><a class="careersLink wtclass linkgeneration" href="/_locale/corporate/careers">Careers</a></li> <li><a class="irLink wtclass linkgeneration" href="/_locale/corporate/investor-relations">Investor Relations</a></li> <li><a class="coLink wtclass linkgeneration" href="/_locale/corporate/community-outreach">Community Outreach</a></li> <li><a class="pteLink wtclass linkgeneration" href="/_locale/corporate/protecting-environment">Protecting the Environment</a></li> <li><a class="newsroomLink wtclass linkgeneration" href="/_locale/corporate/newsroom">Newsroom</a></li> </ul> </div> <p> <script type="text/javascript">// <![CDATA[ $(document).ready(function(){ setSterlingUrlsToHtmlHrefVariables(); $('a.linkgeneration').each(function(){ $(this).attr('href', $(this).attr('href').replace('_locale', languageCode + '-' + countryCode.toLowerCase()).replace('_verticalUrl', currentVerticalUrlTitle).replace('_defaultVerticalUrl', defaultVerticalUrlTitle).replace('_feedbackCMSID',feedbackCMSID)); }); var feedbackOverlayUrl = '/bio-rad/Standalone/FeedbackOverlay.page?standalonePage=true'; $("#feedbackID").click(function(){ openAjaxOverlay(feedbackOverlayUrl,"Feedback"); }); }); // ]]></script> <script type="text/javascript">// <![CDATA[ if($.cookie('evCntryLang')){ (function(){"use strict";var e=null,b="4.0.0", n="10740", additional="", t,r,i;try{t=top.document.referer!==""?encodeURIComponent(top.document.referrer.substring(0,2048)):""}catch(o){t=document.referrer!==null?document.referrer.toString().substring(0,2048):""}try{r=window&&window.top&&document.location&&window.top.location===document.location?document.location:window&&window.top&&window.top.location&&""!==window.top.location?window.top.location:document.location}catch(u){r=document.location}try{i=parent.location.href!==""?encodeURIComponent(parent.location.href.toString().substring(0,2048)):""}catch(a){try{i=r!==null?encodeURIComponent(r.toString().substring(0,2048)):""}catch(f){i=""}}var l,c=document.createElement("script"),h=null,p=document.getElementsByTagName("script"),d=Number(p.length)-1,v=document.getElementsByTagName("script")[d];if(typeof l==="undefined"){l=Math.floor(Math.random()*1e17)}h="dx.steelhousemedia.com/spx?"+"dxver="+b+"&shaid="+n+"&tdr="+t+"&plh="+i+"&cb="+l+additional;c.type="text/javascript";c.src=("https:"===document.location.protocol?"https://":"http://")+h;v.parentNode.insertBefore(c,v)})() } // ]]></script> </p> /webroot/web/html footer_page_b2c_en_US.html /webroot/web/html/footer_page_b2c_en_US.html Karen Moss Footer page Footer 03/26/14 02:17 PM 11/27/23 02:18 PM US en GNL /GNL N 0 en-us Home <script type="text/javascript">$(document).ready(function() { $(".footer-nav > a:nth-child(3)").after(" | <a href='javascript:void(0)' id='regionlink'>Web Accessibility</a>"); var region = $("#headlangID .lang strong").html(); $("#regionlink").click(function(){ window.location.replace( "/webroot/web/html/featured/en/web-accessibility.html?Region=" + region );});});</script>Trademarks Site Terms Terms & Conditions Imprint EU Recycle Program Privacy Change Cookie Setting <script type="text/javascript">$(document).ready(function () {$(".links2").append('<style>.social-links-br {float: left;margin-right: 10px;}.social-links-br img {width: 20px;height: 20px;margin-right: 5px}</style><div class="social-links-br"><a class="no-target-style" href="https://www.linkedin.com/company/bio-rad?trk=top_nav_home" target="_blank"><img src="/webroot/web/images/general/icons/linkedin_round_40x40.png" alt="Bio-Rad LinkedIn"></a><a class="no-target-style" href="https://www.youtube.com/user/BioRadLifeScience" target="_blank"><img src="/webroot/web/images/general/icons/youtube-icon-rnd-40x40.png" alt="Bio-Rad YouTube"></a><a class="no-target-style" href="https://twitter.com/BioRadLifeSci" target="_blank"><img src="/webroot/web/images/general/icons/twitter_round_40x40.png" alt="Bio-Rad Twitter"></a><a class="no-target-style" href="https://www.facebook.com/biorad/" target="_blank"><img src="/webroot/web/images/general/icons/facebook-icon-rnd-40x40.png" alt="Bio-Rad Facebook"></a><a class="no-target-style" href="https://www.instagram.com/bioradlabs/" target="_blank"><img src="/webroot/web/images/general/icons/instagram-icon-rnd-40x40.png" alt="Bio-Rad Instagram"></a></div>');});</script>Copyright &copy; {0} Bio-Rad Laboratories, Inc. All rights reserved. This page was last edited on {0} True GTM-MJ2DN2S us US en GNL corporate life-science-research /prd/en/US/direct/biorad?ts=1&cmd=OrdersWorkspaceDisplay /prd/en/US/direct/biorad?ts=1&cmd=QuotesWorkspaceDisplay /prd/en/US/direct/biorad?ts=1&cmd=InvoiceWorkspaceDisplay&_Tab=Invoice false false true false true true 1040988879 LHsYCOu_wQMQz_Ww8AM window.google_tag_params true 272-THL-329 username CartID_ WT_FPC <script type="text/javascript">$.ajax({url: document.location.protocol + '//munchkin.marketo.net/munchkin.js',dataType: 'script',cache: true,success: function() {Munchkin.init('044-CBN-599');}});</script> <script type="text/javascript" src="/evportal/framework/skins/evolution/js/proxyMunchkin.js"></script> 2018