Our mixed-mode chromatography media combine ion exchange and affinity properties. Unique CHT™ ceramic hydroxyapatite and CFT™ ceramic fluoroapatite media offer alternative separation strategies for the removal of organic and inorganic impurities from biomolecules.
Hydroxyapatite contains two types of binding sites, positively charged calcium and negatively charged phosphate groups. These sites aredistributed regularly throughout the crystal structure of the matrix. Solute species dominantly interact through cation exchange via the Schematic representation of CHT binding mechanisms.
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