Congenital Adrenal Hyperplasia (CAH)

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Congenital Adrenal Hyperplasia (CAH)


Bio-Rad offers a quantitative microplate assay for the determination of 17α-hydroxyprogesterone (17-OHP) in neonatal dried blood spot samples, intended for newborn screening for Congenital Adrenal Hyperplasia (CAH). CAH is an inborn error of metabolism that results from an inherited recessive defect in any of the five enzymatic steps required to synthesize cortisol from cholesterol. Complete or partial deficiency of 21-hydroxylase leads to elevated levels of 17-OHP in 90 to 95 percent of all CAH cases.

CAH exists in several forms: Classical [Salt Wasting (SW), Simple Virilizing (SV)], and Non-Classical (NC). If left untreated, the SW form can result in life-threatening adrenal crises within the first weeks of life and precocious growth in both sexes. Non-classical CAH may result in persistent slight elevations of 17-OHP from birth with clinical manifestations occurring later in life.

The Bio-Rad Quantase Neonatal CAH assay is free of background interferences common with fluorometric assay methods. It is easily automated, and can be performed with any microplate reader. Each kit includes all necessary reagents.

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Microplate Neonatal 17-OHP Assay

532-5402
Quantitative assay for the determination of 17α-hydroxyprogesterone (17-OHP) in neonatal dried blood spot samples (480 tests)

1 5325402 /templatedata/internet/product_SKU/data/CDG/Newborn-Screening/Congenital-Adrenal-Hyperplasia-CAH/532-5402_en_1320569831_1484.xml 5325402 07/29/11 5:00 PM N en 07/29/21 5:00 PM true true internet/product_SKU AE,AI,AL,AM,AR,AT,AU,AZ,BA,BD,BE,BF,BG,BH,BN,BO,BR,BW,CA,CH,CL,CM,CN,CO,CR,CY,CZ,DE,DK,DO,DZ,EC,EE,EG,EH,ER,ES,ET,FI,FM,FO,FR,GA,GE,GF,GH,GP,GR,GT,GU,HK,HN,HR,HT,HU,ID,IE,IL,IN,IS,IT,JM,JO,JP,KE,KH,KR,KW,KZ,LB,LI,LK,LT,LU,LV,MA,MD,MG,MK,ML,MO,MQ,MS,MT,MU,MX,MY,NG,NI,NL,NO,NP,NZ,OM,PA,PE,PF,PG,PH,PK,PL,PR,PS,PT,PW,PY,QA,RO,RS,RU,SA,SB,SE,SG,SI,SK,SN,ST,SV,TG,TH,TN,TO,TR,TT,TW,TZ,UA,UG,UK,US,UY,UZ,VA,VE,VU,XK,YE,ZA CDG 2017-11-14 07:06:47 5325402-microplate-neonatal-17-ohp-assay 5325402 Microplate Neonatal 17-OHP Assay Microplate Neonatal 17-OHP Assay Quantitative assay for the determination of 17&alpha;-hydroxyprogesterone (17-OHP) in neonatal dried blood spot samples (480 tests) /webroot/web/images/cdg/products/newborn_screening/sku_thumb/global/nbs_532_5402_tn.jpg /webroot/web/images/cdg/products/newborn_screening/sku_view/global/nbs_532_5402_view.jpg /webroot/web/images/cdg/products/newborn_screening/sku_feature/global/nbs_532_5402_feature.jpg Microplate Neonatal 17-OHP Assay Alex Samodurov Microplate Neonatal 17-OHP Assay 532-5402, newborn screening, congenital adrenal hyperplasia, cah, microplate neonatal 17-ohp assay 07/29/11 5:00 PM 07/29/21 5:00 PM AE,AI,AL,AM,AR,AT,AU,AZ,BA,BD,BE,BF,BG,BH,BN,BO,BR,BW,CA,CH,CL,CM,CN,CO,CR,CY,CZ,DE,DK,DO,DZ,EC,EE,EG,EH,ER,ES,ET,FI,FM,FO,FR,GA,GE,GF,GH,GP,GR,GT,GU,HK,HN,HR,HT,HU,ID,IE,IL,IN,IS,IT,JM,JO,JP,KE,KH,KR,KW,KZ,LB,LI,LK,LT,LU,LV,MA,MD,MG,MK,ML,MO,MQ,MS,MT,MU,MX,MY,NG,NI,NL,NO,NP,NZ,OM,PA,PE,PF,PG,PH,PK,PL,PR,PS,PT,PW,PY,QA,RO,RS,RU,SA,SB,SE,SG,SI,SK,SN,ST,SV,TG,TH,TN,TO,TR,TT,TW,TZ,UA,UG,UK,US,UY,UZ,VA,VE,VU,XK,YE,ZA en CDG /CDG/Newborn-Screening/Congenital-Adrenal-Hyperplasia-(CAH) N 0 <p><strong><span class="hidden CA-only" style="color: #ff0000;">Unlicensed for Sale in Canada<br /> Non-homologu&eacute; pour la vente au Canada.</span></strong></p> /webroot/web/html/cdg/products/newborn_screening/sku_view/description/global nbs_532-5402_sku_desc.html /webroot/web/html/cdg/products/newborn_screening/sku_view/description/global/nbs_532-5402_sku_desc.html 0 false false false /prd/en/RU/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=5325402&CartQuote=QT&quantity= true true false null false null /prd/en/RU/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=5325402&AddToDefaultWishList=true&quantity= false false true true false true false true /prd/en/RU/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=5325402&quantity= 532-5402
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