BioFrac™ Fraction Collector



Choose Your Fraction Collector
  NGC™ Fraction Collector BioFrac™ Fraction Collector Model 2110 Fraction Collector
Vessel Type Tube/Rack Capacity Tube/Rack Capacity Tube/Rack Capacity
12–13 mm tube 96 384 90 180 80 80
15–16 mm tube 75 300 60 120
18–20 mm/15 ml tube 70 280 40 80
30 mm/50 ml tube 27 108 6 24
0.5 ml tube 63 252
1.5–2 ml microtube 96 384 42 168 80 80
250 ml bottle 4 16 4 4
96-well plate 2 8 4 4
48-well plate 2 8 4 4
24-well plate 2 8 4 4
12-well plate 4 4
Prep-20 preparative rack 20 40 20 20
Cooling Option Peltier cooling racks, coldroom compatible Ice bath, coldroom compatible Coldroom compatible
Chromatography Instrument Compatibility NGC Chromatography System
  • NGC Chromatography System
  • Biologic DuoFlow™ Medium-Pressure Chromatography System
  • BioLogic™ LP Systems, and Model EP-1 Econo™ Pump
  • Biologic DuoFlow Medium-Pressure Chromatography System
  • BioLogic LP Systems
  • Model EP-1 Econo Pump
Size 42 x 60 x 54.5 cm
(16.5 x 23.6 x 21.5 in)
44.5 x 35.6 x 38.7 cm
(17.5 x 14.0 x 15.2 in)
24 x 33 x 25 cm
(9.4 x 13.0 x 9.8 in)
Weight 13 kg (28.7 lbs) 6.9 kg (15.3 lbs) 2.3 kg (5.1 lbs)
Model 2110 Fraction Collector
Model 2110 Fraction Collector

The Model 2110 fraction collector is a carousel-type fraction collector capable of collecting from 1 drop (~50 µL) to 9 mL fractions in 80 test tubes or microtubes. Collection can be in time, drop, or volume mode when connected to the Model EP-1 Econo pump, BioLogic LP system, or BioLogic DuoFlow system. Small chromatography columns can be mounted to drop forming arm to minimize dead volume. It is coldroom compatible.

BioLogic LP System
BioLogic LP System

The BioLogic system is a low-pressure chromatography system used for biomolecule purification. The peristaltic pump is capable of flow rates ranging from 0.05–40mL/min and a maximum backpressure of 30 psi (2 bar, 0.2 MPa). The system can be hooked up to the Model 2110 or BioFrac fraction collector and is coldroom compatible.

BioLogic DuoFlow Systems
BioLogic DuoFlow Systems

BioLogic DuoFlow Systems. These are medium pressure laboratory scale chromatography systems for protein purification. These systems are modular, capable of running at high flow rates (0.05–80 ml/min) with back pressures up to 3,500 psi, with pH monitoring, buffer blending, and column scouting capabilities. It can be used in conjunction with a fraction collector for unattended operation.

The BioFrac Fraction Collector is ideal for analytical and preparative chromatography applications; it's easy to program and can be used for basic or complex fraction collection schemes at flow rates ≤100 ml/min. Available as a stand-alone fraction collector or as a component of the BioLogic DuoFlow™ and BioLogic™ LP Chromatography Systems, the BioFrac Fraction Collector offers flexibility with numerous collection rack options, including both custom and off-the-shelf collection racks.

The custom racks provide a wide range of collection capability, from drops to liters. Off-the-shelf racks extend the versatility of collection schemes and provide cost-effective storage of samples. Off-the-shelf racks are autoclavable, can be easily assembled, and lie flat, using little storage space.

Key features include:

  • Collection in time or drop mode (or volume mode when connected to a BioLogic DuoFlow System, BioLogic LP System, or Econo Gradient Pump)
  • Collection of peaks by peak detection, time windows (up to 20), or a combination of both
  • Drop arm movement in an x, y motion over each collection vessel; column, row, or serpentine pattern option available for microplates or Titertube® Micro Test Tubes
  • Dispenser arm that is manually adjustable to tube heights ≤150 mm
  • Numerous off-the-shelf racks to accommodate tubes (12–20 mm diameter), Eppendorf or other microtubes (0.5, 1.5, or 2.0 ml), or scintillation vials
  • Multirun feature that allows overlay of fractions
  • Highly reliable, quiet, problem-free operation with minimal maintenance requirements
  • Optional BioFrac Ice Bath/Microplate Rack with tube grips that hold tubes firmly in any position; ice bath rack allows cooling of 13 mm tubes or serves as a rack for microplates and tubes that adhere to SBS standards
  • Optional BioFrac Prep-20 Preparative Rack with up to 20 collection ports for collection from bottles to carboys
  • Optional microplate drophead kit for precise collection of small volumes into microplates
Time 0.01–99,999 min
Drop 1–99,999 drops, flow rate ≤5.0ml/min
Volume 0.02–99,999 ml
Collection mode Time, drop, time windows (up to 20 windows), peak detection (threshold), time windows plus peak detection, volume (flow rate ≤100 ml/min)
Peak detection Threshold, including slope detection algorithm for collection of double peaks above a set threshold
Detector input ±0–100 mV or ±0–1 V
Wetted parts All nonmetal, including Tefzel, PEEK
Dimensions (W x D x H) 44.5 x 35.6 x 38.7 cm (17.5 x 14.0 x 15.2")
Weight 6.9 kg (15.3 lb)
Sample throughput 2–3 tubes per sec (test tube change times: ~330 ms with 13 mm tubes, ~450 ms with 18 mm tubes)
Collection basis 1–999 drops in 1 drop increments, 0.05–9.99 min in 0.01 min increments, 10.0–99.9 min in 0.1 min increments
Construction Case and carousel, polypropylene; front panel, hard-coated polycarbonate
Drop former Silicone rubber
Waste outlet tube Polyurethane
Operating temperature 4–40°C
Safety Meets IEC 61010 and CSA 22.2 certification

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BioFrac™ Fraction Collector

100/240 V, fraction collector, includes power cord, rack set F1 (2 x flatpack, 13 mm), BioFrac Diverter Valve, fittings kit

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Number Description Options
4006211 Instruction Manual, BioFrac Fraction Collector User Guide, Rev C Click to download
4106233 Instruction Manual, BioFrac™ Microplate Drop Head Kit, Rev A Click to download
4106195 Instruction Manual, BioFrac™ H4-High Fraction Collector Racks, Rev A Click to download
4106193 Instruction Manual, BioFrac H4 Fraction Collection Racks, Rev A Click to download
4106192 Instruction Manual, BioFrac H3 Fraction Collection Racks, Rev A Click to download
4106191 Instruction Manual, BioFrac H2 Fraction Collection Racks, Rev A Click to download
4106190 Instruction Manual, BioFrac™ H1 Fraction Collection Racks, Rev A Click to download
4106183 Instruction Manual, BioFrac Fraction Collector Diverter Valve, Rev A Click to download
4106186 Instruction Manual, BioFrac Fittings Kit, Rev C Click to download
4106189 Instruction Manual, BioFrac™ F3 Fraction Collection Racks, Rev A Click to download
4106188 Instruction Manual, BioFrac™ F2 Fraction Collection Racks, Rev A Click to download
4106187 Instruction Manual, BioFrac™ F1 Fraction Collection Racks, Rev A Click to download
2711 BioFrac™ Fraction Collector Brochure Insert, Rev C Click to download [ Add to Cart (Free) ]