Bio-Plex Pro™ RBM Rat Kidney Toxicity Assays

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Bio-Plex Pro™ RBM Rat Kidney Toxicity Assays

Overview

Available Bio-Plex Pro™ RBM Rat Kidney Toxicity Assays
Rat Kidney Toxicity Panel 1
(171-KTR1CK)
Analyte Bead Region
Clusterin 12
IL-18 21
KIM-1 20
MCP-1 15
Osteopontin 52
Rat Kidney Toxicity Panel 2
(171-KTR2CK)
Analyte Bead Region
B2M 22
Calbindin 62
Cystatin C 44
NGAL 46
Rat Kidney Toxicity Albumin Kit
(171-KTR3CK)
Analyte Bead Region
Albumin 30
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Bio-Plex® Technology and Applications
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The Bio-Plex Pro RBM kidney toxicity assays, developed in partnership with Myriad RBM, comprise a highly relevant set of biomarkers for early detection and characterization of kidney toxicity/injury. Myriad RBM’s close collaboration with the Predictive Safety Testing Consortium (PSTC), FDA, and European Medicines Evaluation Agency (EMEA) was instrumental in the selection of markers found in these panels.

The assays are built on magnetic beads to enable robust quantification of multiple proteins in rat urine samples, providing valuable information throughout drug development — from lead optimization to preclinical and clinical protocol decision making. Assays are offered as premixed all-in-one kits for research involving:

  • Drug-induced kidney toxicity
  • Diabetes
  • High blood pressure
  • Glomerulonephritis
  • Polycystic kidney disease
  • Chronic infection
  • SLE (lupus) and other autoimmune disorders

Bio-Plex Pro RBM rat kidney toxicity assays are available as two panels and an albumin kit:

    Panel 1
  • Clusterin
  • IL-18
  • KIM-1
  • MCP-1
  • Osteopontin
    Panel 2
  • B2M
  • Calbindin
  • Cystatin C
  • NGAL
    Albumin Kit
  • Albumin

Based on 6.5 µm magnetic beads, these assay panels are compatible with both vacuum and magnetic wash stations. Magnetic washing simplifies plate processing, provides increased throughput, and results in decreased variability and increased reproducibility.

Key Features

  • Optimized for high precision and lot-to-lot reproducibility of sample measurements
  • Magnetic beads for simplified plate processing
  • 2-level quality controls with lot-specific ranges
  • Assay quick guide to get you started right away
  • High-quality design ensures robust and reproducible measurement of nephrotoxicity biomarkers in human, rat, and canine urine samples

Ordering Options

Premixed all-in-one kits

Instrument Compatibility

More Information

See how Bio-Plex instruments and assays benefit researchers studying heart disease, leukemia, melanoma, and other cancers.

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Bio-Plex® Handheld Magnetic Washer

171020100
Includes magnetic washer and adjustment hex tools for use in manual wash steps for all Bio-Plex Magnetic Assays

171020100 /templatedata/internet/product_SKU/data/LSR/Bio-Plex-Suspension-Array-Syst/Bio-Plex-Instruments/171-020100_1326308046.xml 171020100 /default/main/bio-rad/WORKAREA/default 01/11/12 10:16 AM en_US jal7kci7 2017-11-14 07:07:44 true true internet/product_SKU jal7kci7 templatedata/internet/product_SKU/data/LSR/Bio-Plex-Suspension-Array-Syst/Bio-Plex-Instruments/171-020100_1326308046.xml LSR 2018-03-15 23:58:54 /default/main/bio-rad/STAGING N /default/main/bio-rad en 01/11/22 10:53 AM 1520475221661 AE,AI,AL,AM,AR,AT,AU,AZ,BA,BD,BE,BF,BG,BH,BN,BO,BR,BW,CA,CH,CL,CM,CN,CO,CR,CY,CZ,DE,DK,DO,DZ,EC,EE,EG,EH,ER,ES,ET,FI,FM,FO,FR,GA,GE,GF,GH,GP,GR,GT,GU,HK,HN,HR,HT,HU,ID,IE,IL,IN,IS,IT,JM,JO,JP,KE,KH,KR,KW,KZ,LB,LI,LK,LT,LU,LV,MA,MD,MG,MK,ML,MO,MQ,MS,MT,MU,MX,MY,NG,NI,NL,NO,NP,NZ,OM,PA,PE,PF,PG,PH,PK,PL,PR,PS,PT,PW,PY,QA,RO,RS,RU,SA,SB,SE,SG,SI,SK,SN,ST,SV,TG,TH,TN,TO,TR,TT,TW,TZ,UA,UG,UK,US,UY,UZ,VA,VE,VU,XK,YE,ZA 2018-03-15 23:58:54 /default/main/bio-rad/WORKAREA/default/templatedata/internet/product_SKU/data/LSR/Bio-Plex-Suspension-Array-Syst/Bio-Plex-Instruments/171-020100_1326308046.xml templatedata/internet/product_SKU/data/LSR/Bio-Plex-Suspension-Array-Syst/Bio-Plex-Instruments/171-020100_1326308046.xml 171020100-bio-plex-handheld-magnetic-washer 171020100 Bio-Plex Hand Held Magnetic Washer Bio-Plex<sup>&reg;</sup> Handheld Magnetic Washer Includes magnetic washer and adjustment hex tools for use in manual wash steps for all Bio-Plex Magnetic Assays Includes magnetic washer and adjustment hex tools for use in manual wash steps for all Bio-Plex Magnetic Assays /webroot/web/images/lsr/products/bioplex_suspension_array/sku_thumb/global/171-020100_tn.jpg /webroot/web/images/lsr/products/bioplex_suspension_array/sku_view/global/171-020100_view.jpg Amy Gumiran Bio-Plex Hand Held Magnetic Washer Includes magnetic washer and adjustment hex tools for use in manual wash steps for all Bio-Plex Magnetic Assays 171020100, bio-plex, handheld, magnetic, washer, adjustment, hex, tools, manual, wash, assays, immunoassays, singleplex, multiplex 01/11/12 10:16 AM 01/11/22 10:53 AM AE,AI,AL,AM,AR,AT,AU,AZ,BA,BD,BE,BF,BG,BH,BN,BO,BR,BW,CA,CH,CL,CM,CN,CO,CR,CY,CZ,DE,DK,DO,DZ,EC,EE,EG,EH,ER,ES,ET,FI,FM,FO,FR,GA,GE,GF,GH,GP,GR,GT,GU,HK,HN,HR,HT,HU,ID,IE,IL,IN,IS,IT,JM,JO,JP,KE,KH,KR,KW,KZ,LB,LI,LK,LT,LU,LV,MA,MD,MG,MK,ML,MO,MQ,MS,MT,MU,MX,MY,NG,NI,NL,NO,NP,NZ,OM,PA,PE,PF,PG,PH,PK,PL,PR,PS,PT,PW,PY,QA,RO,RS,RU,SA,SB,SE,SG,SI,SK,SN,ST,SV,TG,TH,TN,TO,TR,TT,TW,TZ,UA,UG,UK,US,UY,UZ,VA,VE,VU,XK,YE,ZA en LSR /LSR/Bio-Plex-Suspension-Array-Syst/Bio-Plex-Instruments N 0 1 0 false false false /prd/en/RU/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=171020100&CartQuote=QT&quantity= false true false RUB51,717.00 false null /prd/en/RU/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=171020100&AddToDefaultWishList=true&quantity= true false true true false true false true /prd/en/RU/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=171020100&quantity= 171020100
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Bio-Plex Pro™ Flat Bottom Plates

171025001
Pkg of 40, 96-well plate, for use with Bio-Plex Pro wash stations when using magnetic bead–based assays

171025001 /templatedata/internet/product_SKU/data/LSR/Bio-Plex-Suspension-Array-Syst/Bio-Plex-Pro-Magnetic-Cytokine/171-025001_0921120724536.xml 171025001 /default/main/bio-rad/WORKAREA/default 09/21/09 12:07 PM en_US jal7kch3 2017-11-14 07:07:47 true true internet/product_SKU jal7kch3 templatedata/internet/product_SKU/data/LSR/Bio-Plex-Suspension-Array-Syst/Bio-Plex-Pro-Magnetic-Cytokine/171-025001_0921120724536.xml LSR 2018-03-15 23:58:55 /default/main/bio-rad/STAGING N /default/main/bio-rad en 09/21/19 12:07 PM 1520475221798 AE,AI,AL,AM,AR,AT,AU,AZ,BA,BD,BE,BF,BG,BH,BN,BO,BR,BW,CA,CH,CL,CM,CN,CO,CR,CY,CZ,DE,DK,DO,DZ,EC,EE,EG,EH,ER,ES,ET,FI,FM,FO,FR,GA,GE,GF,GH,GP,GR,GT,GU,HK,HN,HR,HT,HU,ID,IE,IL,IN,IS,IT,JM,JO,JP,KE,KH,KR,KW,KZ,LB,LI,LK,LT,LU,LV,MA,MD,MG,MK,ML,MO,MQ,MS,MT,MU,MX,MY,NG,NI,NL,NO,NP,NZ,OM,PA,PE,PF,PG,PH,PK,PL,PR,PS,PT,PW,PY,QA,RO,RS,RU,SA,SB,SE,SG,SI,SK,SN,ST,SV,TG,TH,TN,TO,TR,TT,TW,TZ,UA,UG,UK,US,UY,UZ,VA,VE,VU,XK,YE,ZA 2018-03-15 23:58:55 /default/main/bio-rad/WORKAREA/default/templatedata/internet/product_SKU/data/LSR/Bio-Plex-Suspension-Array-Syst/Bio-Plex-Pro-Magnetic-Cytokine/171-025001_0921120724536.xml templatedata/internet/product_SKU/data/LSR/Bio-Plex-Suspension-Array-Syst/Bio-Plex-Pro-Magnetic-Cytokine/171-025001_0921120724536.xml 171025001-bio-plex-pro-flat-bottom-plates 171025001 Bio-Plex Pro Flat Bottom Plates Bio-Plex Pro&trade; Flat Bottom Plates Pkg of 40, 96-well plate, for use with Bio-Plex Pro wash stations when using magnetic bead&ndash;based assays Pkg of 40, 96-well plate, for use with Bio-Plex Pro wash stations when using magnetic bead-based assays Pkg of 40, 96-well plate, for use with Bio-Plex Pro wash stations when using magnetic bead&ndash;based assays /webroot/web/images/lsr/products/bioplex_suspension_array/sku_thumb/global/171-025001b_tn.jpg /webroot/web/images/lsr/products/bioplex_suspension_array/sku_view/global/171-025001b_view.jpg /webroot/web/images/lsr/products/bioplex_suspension_array/sku_feature/global/171-025001b_feature.jpg RepEx 171-025001 Pkg of 40, 96-well plate, for use with Bio-Plex Pro wash stations when using magnetic bead-based assays 171025001, bio-plex, pro, flat, bottom, plates, wash, stations, bioplex, multiplex, singleplex, bead-based, assay, assays, immunoassay, coupled, magnetic, beads, detection 09/21/09 12:07 PM 09/21/19 12:07 PM AE,AI,AL,AM,AR,AT,AU,AZ,BA,BD,BE,BF,BG,BH,BN,BO,BR,BW,CA,CH,CL,CM,CN,CO,CR,CY,CZ,DE,DK,DO,DZ,EC,EE,EG,EH,ER,ES,ET,FI,FM,FO,FR,GA,GE,GF,GH,GP,GR,GT,GU,HK,HN,HR,HT,HU,ID,IE,IL,IN,IS,IT,JM,JO,JP,KE,KH,KR,KW,KZ,LB,LI,LK,LT,LU,LV,MA,MD,MG,MK,ML,MO,MQ,MS,MT,MU,MX,MY,NG,NI,NL,NO,NP,NZ,OM,PA,PE,PF,PG,PH,PK,PL,PR,PS,PT,PW,PY,QA,RO,RS,RU,SA,SB,SE,SG,SI,SK,SN,ST,SV,TG,TH,TN,TO,TR,TT,TW,TZ,UA,UG,UK,US,UY,UZ,VA,VE,VU,XK,YE,ZA en LSR /LSR/Bio-Plex-Suspension-Array-Syst/Bio-Plex-Pro-Magnetic-Cytokine N 0 30034376 /templatedata/internet/product_SKU/data/LSR/Bio-Plex-Suspension-Array-Syst/Bio-Plex-Instruments/300-34376_0921120736052.xml false false false /prd/en/RU/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=171025001&CartQuote=QT&quantity= false true false RUB13,727.00 false null /prd/en/RU/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=171025001&AddToDefaultWishList=true&quantity= true false true true false true false true /prd/en/RU/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=171025001&quantity= 171025001
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Bio-Plex Pro™ Wash Station

30034376
Microplate wash station for magnetic bead–based assays, includes magnetic plate carrier, waste bottle, 2 buffer bottles

30034376 /templatedata/internet/product_SKU/data/LSR/Bio-Plex-Suspension-Array-Syst/Bio-Plex-Instruments/300-34376_0921120736052.xml 30034376 /default/main/bio-rad/WORKAREA/default 09/21/09 12:07 PM en_US jal7kchp 2017-11-14 07:07:44 true true internet/product_SKU jal7kchp templatedata/internet/product_SKU/data/LSR/Bio-Plex-Suspension-Array-Syst/Bio-Plex-Instruments/300-34376_0921120736052.xml LSR 2018-03-15 23:58:55 /default/main/bio-rad/STAGING N /default/main/bio-rad en 09/21/19 12:07 PM 1520475221706 AE,AI,AL,AM,AR,AT,AU,AZ,BA,BD,BE,BF,BG,BH,BN,BO,BR,BW,CA,CH,CL,CM,CN,CO,CR,CY,CZ,DE,DK,DO,DZ,EC,EE,EG,EH,ER,ES,ET,FI,FM,FO,FR,GA,GE,GF,GH,GP,GR,GT,GU,HK,HN,HR,HT,HU,ID,IE,IL,IN,IS,IT,JM,JO,JP,KE,KH,KR,KW,KZ,LB,LI,LK,LT,LU,LV,MA,MD,MG,MK,ML,MO,MQ,MS,MT,MU,MX,MY,NG,NI,NL,NO,NP,NZ,OM,PA,PE,PF,PG,PH,PK,PL,PR,PS,PT,PW,PY,QA,RO,RS,RU,SA,SB,SE,SG,SI,SK,SN,ST,SV,TG,TH,TN,TO,TR,TT,TW,TZ,UA,UG,UK,US,UY,UZ,VA,VE,VU,XK,YE,ZA 2018-03-15 23:58:55 /default/main/bio-rad/WORKAREA/default/templatedata/internet/product_SKU/data/LSR/Bio-Plex-Suspension-Array-Syst/Bio-Plex-Instruments/300-34376_0921120736052.xml templatedata/internet/product_SKU/data/LSR/Bio-Plex-Suspension-Array-Syst/Bio-Plex-Instruments/300-34376_0921120736052.xml 30034376-bio-plex-pro-wash-station 30034376 Bio-Plex Pro Wash Station Bio-Plex Pro&trade; Wash Station Microplate wash station for magnetic bead&ndash;based assays, includes magnetic plate carrier, waste bottle, 2 buffer bottles Microplate wash station for magnetic bead based assays, includes magnetic plate carrier, waste bottle, 2 liquid bottles Microplate wash station for magnetic bead&ndash; based assays, includes magnetic plate carrier, waste bottle, 2 buffer bottles /webroot/web/images/lsr/products/bioplex_suspension_array/sku_thumb/global/300-34376_tn.jpg /webroot/web/images/lsr/products/bioplex_suspension_array/sku_view/global/300-34376_view.jpg /webroot/web/images/lsr/products/bioplex_suspension_array/sku_feature/global/300-34376_feature.jpg RepEx 300-34376 Microplate wash station for magnetic bead&ndash; based assays, includes magnetic plate carrier, waste bottle, 2 liquid bottles 30034376, bio-plex, pro, wash, station, microplate, washing, magnetic-based, assays, plate, carrier 09/21/09 12:07 PM 09/21/19 12:07 PM AE,AI,AL,AM,AR,AT,AU,AZ,BA,BD,BE,BF,BG,BH,BN,BO,BR,BW,CA,CH,CL,CM,CN,CO,CR,CY,CZ,DE,DK,DO,DZ,EC,EE,EG,EH,ER,ES,ET,FI,FM,FO,FR,GA,GE,GF,GH,GP,GR,GT,GU,HK,HN,HR,HT,HU,ID,IE,IL,IN,IS,IT,JM,JO,JP,KE,KH,KR,KW,KZ,LB,LI,LK,LT,LU,LV,MA,MD,MG,MK,ML,MO,MQ,MS,MT,MU,MX,MY,NG,NI,NL,NO,NP,NZ,OM,PA,PE,PF,PG,PH,PK,PL,PR,PS,PT,PW,PY,QA,RO,RS,RU,SA,SB,SE,SG,SI,SK,SN,ST,SV,TG,TH,TN,TO,TR,TT,TW,TZ,UA,UG,UK,US,UY,UZ,VA,VE,VU,XK,YE,ZA en LSR /LSR/Bio-Plex-Suspension-Array-Syst/Bio-Plex-Instruments N 0 false false false /prd/en/RU/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=30034376&CartQuote=QT&quantity= false true false RUB662,680.00 false null /prd/en/RU/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=30034376&AddToDefaultWishList=true&quantity= false false true true false true false true /prd/en/RU/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=30034376&quantity= 30034376
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Number Description Options
6458 Bio-Plex Success Guide/Assay Sample Prep, Rev B Click to download
6335 Bio-Plex® Multiplex Immunoassays Analyte Guide, Rev E Click to download [ Add to Cart (Free) ]
10028258 Instruction Manual, Bio-Plex Pro RBM Kidney Toxicity Assays, Rev A Click to download
10028259 Instruction Manual, Bio-Plex Pro RBM Kidney Toxicity Assays Quick Guide, Rev B Click to download
6347 Bio-Plex Pro RBM Assays Product Information Sheet, Rev A Click to download [ Add to Cart (Free) ]
6400 Profiling of Human, Canine, and Rat Urine Samples Using Bio-Plex Pro RBM Kidney Toxicity Assay, Rev A Click to download

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