QXDx™ ddPCR™ System

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QXDx™ ddPCR™ System


The QXDx ddPCR System is Bio-Rad’s Droplet Digital™ PCR System approved for use in a regulatory environment. The system, which includes the QXDx™ Droplet Generator and QXDx Droplet Reader, provides precise and absolute quantification of target DNA or RNA molecules in a wide variety of in vitro diagnostics (IVD)* applications.

The QXDx ddPCR System enables up to 8 reactions at a time, whereas its automated counterpart, the QXDx™ AutoDG™ ddPCR™ System, is optimized for higher throughput needs.

Note: Until the phasing in of its proprietary name, this product will be available under the registered name QX200™ Droplet Digital™ PCR Dx System. Find out more.

Features and Benefits

  • CE marking — quality product with great sensitivity and reproducibility
  • Absolute quantification — provides an absolute count of target DNA copies per input without the need for standard curves
  • Highest precision and sensitivity — enriched template concentration in target-positive droplets enabling higher precision and sensitivity than NGS and real-time PCR
  • Removal of PCR efficiency bias — error rates are reduced by removing the reliance on amplification efficiency of qPCR due to high tolerance of PCR inhibitors

Applications and Uses

  • Copy number variation
  • Rare sequence detection
  • Gene expression analysis
  • Next-generation sequencing (NGS) library quantification
  • Viral load determination
  • Absolute quantification
  • Rare mutant detection
  • miRNA analysis
  • GMO detection

Included Components

  • QXDx Droplet Generator
  • QXDx Droplet Reader
  • QuantaSoft™ Software

Related Products

The QXDx ddPCR System is used and validated with the following thermal cycler specifications:

  • Accuracy: ±0.2°C
  • Uniformity: ±0.4°C well-to-well within 10 sec
  • Adjustable ramp capability with required ramp rate: up to 2°C/sec
  • Temperature range: 0–100°C

The C1000 Touch™ Thermal Cycler with 96–Deep Well Reaction Module (1851197) was used during the development and validation efforts of all QXDx products.

Related Categories

Digital PCR

*Legal Notice
This product and/or its use is covered by claims of U.S. patents, and/or pending U.S. and non-U.S. patent applications owned by or under license to Bio-Rad Laboratories, Inc. Purchase of the product includes a limited, non-transferable right under such intellectual property for use of the product for internal research and diagnostic purposes only. No rights are granted for use of the product for commercial applications of any kind, including but not limited to manufacturing, quality control, or commercial services, such as contract services or fee for services. Information concerning a license for such uses can be obtained from Bio-Rad Laboratories. It is the responsibility of the purchaser/end user to acquire any additional intellectual property rights that may be required.

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Waste Electrical and Electronic Equipment ("WEEE Directive")

This product contains electrical or electronic material. Learn more about Bio-Rad's EU Recycle Program

Waste Electrical and Electronic Equipment ("WEEE Directive")

This product contains electrical or electronic material. Learn more about Bio-Rad's EU Recycle Program

Waste Electrical and Electronic Equipment ("WEEE Directive")

This product contains electrical or electronic material. Learn more about Bio-Rad's EU Recycle Program

Waste Electrical and Electronic Equipment ("WEEE Directive")

This product contains electrical or electronic material. Learn more about Bio-Rad's EU Recycle Program

QXDx™ ddPCR™ System

17000034
Droplet Digital™ PCR System for IVD, includes manual droplet generator, droplet reader, laptop computer, software, associated component consumables, for probe-based digital PCR applications

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QXDx™ Droplet Generator

12001049
Droplet generator for probe-based digital PCR applications, for use with the QXDx™ ddPCR™ System

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QXDx™ Droplet Reader

12001045
Droplet reader for probe-based digital PCR applications, for use with the QXDx™ ddPCR™ and QXDx™ AutoDG™ ddPCR™ Systems

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PX1™ PCR Plate Sealer

1814000
PCR plate sealer, includes heat sealing instrument, plate support block that holds 96-well and 384-well plates, sealing frame, power cord

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Number Description Options
AW16000573 Instruction Manual, QXDx™ Droplet Reader and QuantaSoft™ Software Click to download
AW16000648 Instruction Manual, QXDx™ Droplet Generator Click to download