RAPsyD by HPLC (Reversed Phase)

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RAPsyD by HPLC (Reversed Phase)

Bio-Rad's Rapid Analysis of Psychiatric Drugs (RAPsyD) provides reliable, fast and easy simultaneous, quantitative measurement of clozapine, olanzapine, quetiapine, risperidone, and their pharmacologically active metabolites. The antipsychotics are extracted and separated with an HPLC method that involves online column switching between an extraction cartridge and an analytical column. This application is compatible with Bio-Rad's Benzo/TCA by HPLC assay, as both tests use the same analytical columns, extraction cartridges and mobile phases.

With its fully automated HPLC method, the RAPsyD assay allows for online sample preparation and does not require manual pipetting steps, making it a time-saving and convenient method. RAPsyD by HPLC gives physicians an efficient tool for initial determination of dosage and for subsequent therapeutic drug monitoring.

Test characteristics:

  • Principle: Isocratic HPLC Method
  • Duration of the chromatography: 25 min.
  • Sample volume: 100 µL serum or plasma
  • Flow rate: 1.3 mL/min (clozapine, olanzapine, quetiapine); 0.8 mL/min (risperidone)
  • UV Detection: 254 nm (clozapine, olanzapine, quetiapine); 278 nm (risperidone)

 

RAPsyD by HPLC Reagent Kit
RAPsyD by HPLC Reagent Kit

195-6600
Reagents for rapid analysis of antipsychotic drugs (clozapine, olanzapine, perazine, quetiapine, risperidone) in serum or plasma by HPLC (200 tests)

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Standard Extraction Set
Standard Extraction Set

195-6634
Standard extraction set for RAPsyD by HPLC (1 unit)

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Analytical Column for TDM by HPLC
Analytical Column for TDM by HPLC

195-6684
Analytical column and microguard cartridge for therapeutic drug monitoring by Benzodiazepines and Tricyclics and RAPsyD HPLC assays (600/2 x 250 injections)

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Micro-Guard Cartridge Holder

195-5030
1 holder for high performance liquid chromatography guard cartridge

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Holder for Extraction Cartridge
Holder for Extraction Cartridge

270-0613
Holder for extraction cartridge used to prepare samples for online reverse-phase HPLC assays (1 x 1)

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Prefilter Holder, Online Method
Prefilter Holder, Online Method

195-6682
Prefilter holder for HPLC assay; online method (1 unit)

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TDM by HPLC Mobile Phase 1 Set
TDM by HPLC Mobile Phase 1 Set

195-6686
Mobile phase 1 for therapeutic drug monitoring by Benzodiazepines and Tricyclics and RAPsyD HPLC (4 x 1 L)

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TDM by HPLC Mobile Phase 2 Set
TDM by HPLC Mobile Phase 2 Set

195-6687
Mobile phase 2 for therapeutic drug monitoring by Benzodiazepines and Tricyclics and RAPsyD HPLC (4 x 1 L)

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Extraction Cartridges (Includes 2 Prefilters)
Extraction Cartridges (Includes 2 Prefilters)

195-6685
Extraction cartridge for therapeutic drug monitoring by Benzodiazepines and Tricyclics and RAPsyD HPLC assays (1 x 100 injections)

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Calibrator A (mono-level) for RAPsyD by HPLC Reagent Kit
Calibrator A (mono-level) for RAPsyD by HPLC Reagent Kit

195-6607
Calibrators (clozapine, norclozapine, olanzapine) for HPLC of antipsychotics (5 mL)

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Calibrator C (mono-level) for RAPsyD by HPLC Reagent Kit
Calibrator C (mono-level) for RAPsyD by HPLC Reagent Kit

195-6606
Calibrators (isperidone, 9-OH risperidone, ziprasidone) for HPLC of antipsychotics (5 mL)

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Control Set A (bi-level) for RAPsyD by HPLC Reagent Kit
Control Set A (bi-level) for RAPsyD by HPLC Reagent Kit

195-6677
Bi-level control set containing clozapine, norclozapine, olanzapine and quetiapine for use with RAPsyD by HPLC assay (2 x 2 x 5 mL)

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Control Set C (bi-level) for RAPsyD by HPLC Reagent Kit
Control Set C (bi-level) for RAPsyD by HPLC Reagent Kit

195-6678
Bi-level control set containing risperidone and 9-OH risperidone for use with RAPsyD by HPLC assay (2 x 2 x 5 mL)

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