Rabies Testing

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Overview


History

On July 6, 1885, Louis Pasteur was the first person to treat a patient bitten by a rabid animal by injecting extracts of virulent marrow in order to trigger the immune response: vaccination was born.

Over the years, the Institut Pasteur in Paris has maintained its leading and innovative role in the field of rabies treatment. Today, the reagents produced and marketed by Bio-Rad are the result of Institut Pasteur research and provide a reference for the detection and assaying of rabies antigens and antibodies.


The Rabies Virus

The rabies virus is a highly neurotropic virus that causes encephalitis in mammals and is usually fatal. It is still present in virtually all regions of the world.

Worldwide, the World Health Organization (WHO) estimates the number of human deaths to be about 50,000 annually, and over 94% of these deaths are caused by rabid dogs. Efforts to control rabies in dogs include the management of dog populations and vaccination programs.


International Organization and Regulations

The World Organization for Animal Health (OIE) is an international organization providing governments with recommendations on vaccination and diagnosis of major animal diseases, especially zoonoses.

Both the OIE and the WHO are the references for rabies control and eradication programs.

As an example, European regulations apply to international movements of domestic carnivores from rabies-infected to rabies-free countries; rabies immunization and titration of neutralizing antibody should be carried out in an approved laboratory on a sample within the periods laid down in national regulations. Domestic carnivores are allowed to travel if their serum contains at least 0.5 IU/ml.

Bio-Rad is contributing to these developments with the production of high-quality rabies reagents.


Protocol

Platelia Rabies II Kit ad usum veterinarium

The Platelia Rabies II kit ad usum veterinarium uses an ELISA technique intended for the detection and titration of rabies anti-glycoprotein antibodies in animal sera. Antibody titration in animals is used for:

  • Individual serology for international trade purposes: antibodies are measured to assess the immune response of vaccinated animals (for example, cats and dogs)
  • Confirmation of the vaccination status: control of the antibody response provides an indirect assessment of the effectiveness of oral vaccination campaigns in wildlife animals (for example, foxes)

Platelia Rabies II kit ad usum veterinarium is OIE certified for monitoring the immune status of dogs, cats, and foxes.

Platelia Rabies II Kit

The Platelia Rabies II kit uses an ELISA technique intended for the detection and titration of rabies anti-glycoprotein antibodies in human sera.

Antibody titration in humans is used for:

  • Checking vaccinated people for individual response to immunization
  • Checking vaccinated people who have come in contact with rabid animals, since these individuals are usually revaccinated and submitted to serological titration before entering into the Post Exposure Treatment protocol
Assay type ELISA
Organism Rabies
Platelia Rabies II
Platelia Rabies II

355-1180
192 tests

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Platelia Rabies II Kit ad usum veterinarium #355-0180
Platelia Rabies II Kit ad usum veterinarium

355-0180
ELISA assay for titration of anti-rabies antibodies in animal sera

List Price:   Inquire
Quantity:   Add to Quote
Add to Hot List