Quantity One 1-D Analysis Software

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Overview

Specifications
System Requirements for Quantity One 1-D Analysis Software
  PC Macintosh
Operating system Windows 2000 or Windows XP Mac OS 9.2.2 or Mac OS X 10.3 (except Gel Doc XR)
Processor/model Pentium ≥333 MHz PowerPC G3 or better (except Gel Doc XR)
RAM ≥256 MB ≥256 MB
Hard diskspace ≥3 GB ≥3 GB
Monitor 17", ≥1,024 x 768 resolution (absolutely required), true color 17", ≥1,024 x 768 resolution (absolutely required), millions of colors
USB port Required for the hardware security key Required for the hardware security key
Printer Optional Optional
System Requirements for Gel Doc XR System
  PC Macintosh
FireWire port Free FireWire port or PCI slot required Free FireWire port or PCI slot required
System Requirements for ChemiDoc XRS and VersaDoc Systems
  PC Macintosh
PCI slot Free PCI slot required Free PCI slot required (for compatibility with Mac G5, contact technical support)
System Requirements for PharosFX System
  PC Macintosh
USB-2 USB-2 USB-2
System Requirements for EXQuest Spot Cutter
  PC Macintosh
USB One port required EXQuest spot cutter not supported on Macintosh
Comparison of Quantity One 1-D Analysis Software Features
  Quantity One Quantity One Basic
Acquire images X X
Open TIFF images X X
Export to TIFF X X
Print images X X
Text tool X X
Line tool X X
Auto-align text X  
Volume contour tool X  
Volume freehand tool X  
Volume rectangle tool X X
Volume circle tool X X
Volume array tool X  
Volume report X X
Colors X X
Plot density X X
Multichannel viewer X  
Image stack tool X  
3D viewer X X
Transform X X
Crop X X
Advanced crop X X
Flip X X
Rotate 90 degrees, 180 degrees X X
Custom rotate X X
Frame lanes X  
Detect bands X  
Compare lanes X  
Gaussian model bands X  
Contour X  
Assign MW standards X  
Match bands X  
Show band models X  
Lane report X  
Phylogenetic tree X  
Similarity matrix X  
Automation manager X  
Colony counting X  
Differential display X  
ReadyAgarose 96 Plus wizard X X
21 CFR Part 11 Functionality

Title 21 Code of Federal Regulations (CFR) Part 11 — Electronic Records; Electronic Signatures from the United States' Food and Drug Administration (FDA) provides a standard for regulated companies for data security and integrity, electronic records, and electronic signatures. The regulation is mandatory for the pharmaceutical and biotechnology industry because the regulation affects all drug and pharmaceutical products intended for the US market.

The CFR compliance features are available as optional modules in Quantity One analysis software and PDQuest 2-D analysis software.

System Access

To provide the security required for compliance with the 21 CFR Part 11 regulations, the software's security model is layered on top on the Microsoft Windows operating system (2000 or XP Professional) security functions.

The operating system has to be properly configured; otherwise the system will not be secure and therefore will not be in compliance. The access control of the application includes the following features, based on the Windows domain/workstation:

  • A log-in screen before the application starts
  • Global audit entry for security, failed log-in, time out, signatures
  • Automatic timing out of inactive user after a certain time
  • Display of logged-in user in application window title
  • Allows user groups with different access levels

The access control allows different user groups and different levels of authority:

  • Administrator — system administration and full application access
  • User — full application access
  • Technician — only image acquisition and spot cutting
  • Guest — only viewer mode

Data Security

The accuracy of the electronic copy is confirmed using a secure checksum in Quantity One software. These features are provided to ensure protection of records:

  • The original raw data is saved in a backup file; this backup file is read-only and cannot be modified
  • The data will be saved with the user security of the signed-in user; this will prevent unauthorized users from opening, modifying, or deleting this data
  • Records created on a 21 CFR 11 system cannot be opened on a non-21 CFR 11 system, and vice versa

Audit Trails

Secure time-stamped audit trails are implemented in Quantity One to independently record the date and time of operator entries and actions that create, modify, or delete electronic records. The audit trail can be exported to file, printed, and filtered (that is, to show only signature events).

Interactive audit trail of operator with highlighted entry corresponding to image.

The audit log includes:

  • Time stamp
  • User name
  • Action details
  • User comment (optional)
  • Version of software used

Electronic Signatures

Electronic signature capability allows data files to be previewed and approved prior to further processing. The name, date and time of signature, and the meaning of the signature are stored as part of each electronic record. When a signature is performed, the associated data will be automatically saved and locked. Signed files cannot be changed or overwritten.

Image acquisition from all Bio-Rad imaging systems is simple with Quantity One® 1-D analysis software. The software can acquire, quantitate, and analyze a variety of data, including radioactive, chemiluminescent, fluorescent, and color-stained samples acquired from densitometers, storage phosphor imagers, fluorescence imagers, and gel documentation systems. The software allows automatic configuration of these imaging systems with appropriate filters, lasers, LEDs, and other illumination sources. Its flexible tools allow automated analysis of 1-D electrophoretic gels, western blots, dot blots, slot blots, arrays, and colony counts for fast, high-quality results.

Flexible Lane and Band Analysis

  • Automatic lane and band detection
  • Rapid molecular weight determination with choice of multiple regression models and preset standards
  • Band and lane matching analysis with comparative dendrogram creation
  • Background subtraction correction of gradient gels
  • Purity analyzer

Quick and Easy Quantitation

  • Accurate concentration analysis using sophisticated volume tools (volume box, volume circle, volume contour, or freehand drawing)
  • Local background subtraction for individual bands

Automation Manager allows templates for the following common functions to be saved and run automatically:

  • Recall of lane and sample layouts
  • MW determination
  • Volume overlays
  • Text and line overlays

 Integration with the EXQuest™ Spot Cutter

  • Easy-to-use point-and-click spot cutting of 1-D gels
  • Integrated tools to cut specified bands or entire lanes from 1-D gels
  • Increased accuracy and reproducibility by integrating Quantity One software with the EXQuest spot cutter to cut 1-D gels prior to mass spectrometric identification

Other Functionality

  • Colony counting that discriminates colonies and plaques
  • Array tools to analyze and quantitate dot blots, slot blots, and medium-density arrays
  • Annotation tools to add text and lines
  • Tools for compliance with U.S. FDA 21 CFR Part 11 regulations
  • ReadyAgarose™ precast gel wizard for simplified sample tracking

Quantity One Basic Software

Many of the features listed above are available in Quantity One Basic software. Images can be acquired and analyzed, data shared among colleagues, and images annotated and submitted for journal publication with this free software, which includes the basic functionality. Quantity One Basic is available without a license or password restrictions and can be loaded on an unlimited number of computers. Download the latest version of Quantity One software for your system here.

Quantity One® 1-D Analysis Software

170-9600
1-user license, PC or Mac, image acquisition and analysis software for use with Bio-Rad imaging systems

List Price:   $3,059.00
Quantity:   Add to cart
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Quantity One 1-User Network License

170-9601
1-user network license, PC or Mac, image acquisition and analysis software for use with Molecular Imager systems

List Price:   $4,689.00
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Quantity One 2-User Network License

170-9602
2-user network license, PC or Mac, image acquisition and analysis software for use with Molecular Imager systems

List Price:   $6,273.00
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This product is not available for sale online. Please contact customer service for more information.
 
Quantity One 3-User Network License

170-9603
3-user network license, PC or Mac, image acquisition and analysis software for use with Molecular Imager systems

List Price:   $7,825.00
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Quantity One 4-User Network License

170-9604
4-user network license, PC or Mac, image acquisition and analysis software for use with Molecular Imager systems

List Price:   $8,871.00
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Quantity One 5-User Network License

170-9605
5-user network license, PC or Mac, image acquisition and analysis software for use with Molecular Imager systems

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Quantity One 10-User Network License

170-9606
10-user network license, PC or Mac, image acquisition and analysis software for use with Molecular Imager systems

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Quantity One Add 1 User to Network License

170-9608
Adds one user to existing network license, image acquisition and analysis software for use with Molecular Imager systems

List Price:   $1,486.00
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This product is not available for sale online. Please contact customer service for more information.
 
Quantity One Version Upgrade

170-9610
Software version upgrade, PC or Mac, image acquisition and analysis software for use with Molecular Imager systems

List Price:   $1,189.00
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Quantity One CFR Module

170-9615
Pkg of 1, 21 CFR Part 11 compliance module for use with Quantity One 1-D analysis software (#170-9600)

List Price:   $3,541.00
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Number Description Options
5299 Performance Comparison of the Experion Automated Electrophoresis System and SDS-PAGE for Protein Analysis, Rev B Click to download [ Add to Cart (Free) ]
2752 Applications for Molecular Imager FX™ Systems: Instrument Settings, Rev B Click to download
2597 Three-Color Imaging With the Molecular Imager FX Pro Plus System and Quantity One Software, Rev A Click to download
4100201 Instruction Manual, The Discovery Series Software, Multi-User License Installation, Rev A Click to download
4000126-14 Instruction Manual, The Discovery Series: Quantity One 1-D Analysis Software, Rev A Click to download
2753 Flat Fielding with VersaDoc Imaging Systems Product Information sheet, Rev A Click to download
5888 Bio-Rad Imaging Systems Family Brochure, Rev E Click to download [ Add to Cart (Free) ]