Lyme Borreliosis, a non-contagious infection caused by Borrelia burgdorferi sensu lato, is the most prevalent tick-borne zoonosis and is considered an important emerging infection. In Europe, North America and Far Eastern countries, incidence has increased markedly over the last 10 years.
Infections can be sub-clinical or can result in dermatological, neurological, cardiac or musculoskeletal disorders. Borrelia burgdorferi is extremely sensitive to a large panel of antibiotics. However, if not appropriately treated, Lyme Borreliosis will progress from the early stage "Erythema Migrans" to later and more severe stages. Low specificity of clinical symptoms and high efficiency of antibiotic treatment reinforce the need for accurate diagnostic. Current guidelines recommend using highly sensitive screening assays first, then to retest positive samples with a specific confirmatory method like immunoblot.
Platelia Lyme IgM and IgG are highly sensitive and specific assays for accurate and precise screening of Lyme Borreliosis. Platelia Lyme IgG also allows for diagnosis of Lyme neuroborreliosis.