Macro-Prep CM Media

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Macro-Prep CM weak cation exchange support meets the demands of analytical, semipreparative, and process-scale applications. This rigid, macroporous hydrophilic support provides exceptional capacity, resolution, and throughput in a chemically and mechanically stable form. Macro-Prep CM operates well at low and medium pressures and exhibits minimal volume changes in response to variations in pH or ionic strength. It provides consistent and reproducible results. Advantages of Macro-Prep CM support include:

  • High capacity for biomolecules
  • High resolution of complex biological mixtures
  • Rigid polymer matrix that allows high flow rates at moderate pressures
  • Hydrophilic matrix that reduces nonspecific binding
  • Macroporous beads that enhance access to ionic sites
  • Chemical, mechanical, and thermal stability
Type of ion exchanger Weak cation
Counterion Na+
Total ionic capacity 210±40 µeq/ml
Median particle 50 µm
Storage solution 20% ethanol
Recommended maximum linear flow rate 3,000 cm/hr
Chemical stability  
   1% SDS, 24 hr Yes
   6 M guanidine-HCl, 24 hr Yes
   pH stability 1–12
Volume changes  
   pH 4–10 <1%
   0.1–1.0 M NaCl <4%
Regeneration 1 M NaCl
Autoclavability (121°C, 30 min) Yes
Macro-Prep CM Support

158-0070
25 ml, weak cation exchange chromatography media, 50 μm particle size

List Price:   $79.00
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Macro-Prep CM Support

156-0070
100 ml, weak cation exchange chromatography media, 50 μm particle size

List Price:   $237.00
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Macro-Prep CM Support

156-0071
500 ml, weak cation exchange chromatography media, 50 μm particle size

List Price:   $840.00
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Macro-Prep CM Support

156-0072
5 L, weak cation exchange chromatography media, for analytical, semi-preparative, and process scale applications, 50 μm particle size

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Macro-Prep CM Support

156-0073
10 L, weak cation exchange chromatography media, for analytical, semi-preparative, and process scale applications, 50 μm particle size

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Number Description Options
LIT271 Instruction Manual, Macro-Prep Ion Exchange Supports, Rev D Click to download
5662 Process Chromatography Applications Laboratory Brochure, Rev B Click to download