Macro-Prep® Cation Exchange Resin

Print
Macro-Prep 25 S Cation Exchange Resin - Cation Exchange Resin

Overview

Specifications
Property DEAE High Q High S CM
Type of support Weak anion Strong anion Strong cation Weak cation
Functional ligand –N+(C2H5)2 –N+(CH3)3 –SO3- –COO-
Ionic capacity 175 ±75 µeq/ml 400 ±75 µeq/ml 160 ±40 µeq/ml 210 ±40 µeq/ml
Typcial binding capacity 35 mg BSA/ml 40 mg BSA/ml 70 mg IgG*/ml 35 mg hemoglobin/ml
Counterion Cl- Cl- NA+ NA+
Nominal particle size 50 µm 50 µm 50 µm 50 µm
Nominal pore size 1,000 Å 1,000 Å 1,000 Å 1,000 Å
Recommended maximum linear flow rate 3,000 cm/hr 3,000 cm/hr 3,000 cm/hr 3,000 cm/hr
Chemical stability
    1% SDS, 24 hr Yes Yes Yes Yes
    6 M guanidine-HCl, 24 hr Yes Yes Yes Yes
Volume changes
    pH 4–10 <1% <1% <3% <1%
    0.1–1.0 M NaCl <5% <5% <9% <4%
Autoclavability
(121°C, 80 min)
Yes Yes Yes Yes
pH stability 1–10 1–10 1–12 1–12
Antimicrobial agent 20% ethanol 20% ethanol 20% ethanol 20% ethanol
Regeneration 1 M NaCl 1 M NaCl 1 M NaCl 1 M NaCl

* Human IgG.

Macro-Prep High S strong cation exchange support meets the demands of analytical, semipreparative, and process-scale applications. This rigid, macroporous hydrophilic support provides exceptional capacity, resolution, and throughput in a chemically and mechanically stable form.

All Macro-Prep resin operate well at low and medium pressures and exhibit minimal volume changes in response to variations in pH or ionic strength. These resins provide consistent and reproducible results.

Key Features

  • High capacity for biomolecules
  • High resolution of complex biological mixtures
  • Rigid polymer matrix that allows high flow rates at moderate pressures
  • Hydrophilic matrix that reduces nonspecific binding
  • Macroporous beads that enhance access to ionic sites
  • Chemical, mechanical, and thermal stability

 

Macro-Prep High S Support

158-0030
25 ml, strong cation exchange chromatography media, 50 μm particle size

List Price:   $68.00
Your Price:   Log in
Quantity:   Add to cart
Add to Hot List   Add to Quote
Macro-Prep High S Support #156-0031
Macro-Prep High S Support

156-0030
100 ml, strong cation exchange chromatography media, 50 μm particle size

List Price:   $210.00
Your Price:   Log in
Quantity:   Add to cart
Add to Hot List   Add to Quote
Macro-Prep High S Support #156-0032
Macro-Prep High S Support

156-0031
500 ml, strong cation exchange chromatography media, 50 μm particle size

List Price:   $840.00
Your Price:   Log in
Quantity:   Add to cart
Add to Hot List   Add to Quote
Macro-Prep High S Support #156-0033
Macro-Prep High S Support

156-0032
5 L, strong cation exchange chromatography media, for analytical, semi-preparative, and process scale applications, 50 μm particle size

List Price:   Inquire
Quantity:   Add to Quote
Add to Hot List  
Macro-Prep High S Support

156-0033
10 L, strong cation exchange chromatography media, for analytical, semi-preparative, and process scale applications, 50 μm particle size

List Price:   Inquire
Quantity:   Add to Quote
Add to Hot List  
Number Description Options
2026 Evaluation of Different Approaches for the Chromatographic Purification of Monoclonal Antibodies Click to download
1913 Developing and Scaling Up a Purification Procedure With Two New Ion Exchange Supports (Poster), Rev B Click to download
1985 Clearance of Murine Leukemia Virus From a Chimeric Monoclonal Antibody Using Ion Exchange Chromatography, Rev B. Click to download [ Add to Cart (Free) ]
2292 Macro-Prep Ion Exchange Supports Product Information Sheet, Rev A Click to download
5643 Macro-Prep High S Support Product Information Sheet, Rev A. Click to download [ Add to Cart (Free) ]
LIT271 Instruction Manual, Macro-Prep Ion Exchange Supports, Rev D Click to download