Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency

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Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency

The Quantase G6PD Assay is a rapid, colorimetric assay for the qualitative determination of glucose-6-phosphate dehydrogenase deficiency (G6PD) in dried blood spot specimens. G6PD deficiency is one of the most common hereditary enzyme disorders. The G6PD enzyme is found in most body cells, and its deficiency impairs the stability of red cell membranes, making red cells susceptible to destruction by strong oxidizing agents. Affected persons can develop hemolytic anemia when exposed to certain drugs and foods, such as fava beans. Bio-Rad’s Quantase G6PD assay is free of background interferences associated with fluorometric assay methods. It runs at room temperature and uses dried blood spot specimens, eliminating the need for a red blood cell lysis step.