Gastrointestinal Tumor Antigen (CA 19-9)

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Gastrointestinal Tumor Antigen (CA 19-9)

A large glycoprotein of molecular weight ~210 kD, CA 19-9 is a cell surface antigen located on MUC-1 whose carbohydrate determinant is defined as a sialylated Lewis (a) blood group antigen. Elevated in patients with pancreatic cancer, CA 19-9 is also variably (20–50%) elevated in patients with colorectal, gastric, and hepatocellular cancer.