Cytokeratin-19 Antigen (Cyfra 21-1)

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Cytokeratin-19 Antigen (Cyfra 21-1)

A soluble 40 kD cytokeratin fragment found in the cytoplasm of epithelial cells that is released into the serum following apoptosis. Clinical studies in lung and bronchial cancer patients demonstrate that measuring Cytokeratin 19 levels aid in the diagnosis and follow-up of non-small cell and squamous cell carcinoma of the lung.