Carcinoembryonic Antigen (CEA)

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Carcinoembryonic Antigen (CEA)

CEA is a large glycoprotein (~200 kD) consisting of a single polypeptide chain with varying carbohydrate components. Elevated CEA levels can be detected in smokers, patients with colorectal polyps, pancreatitis, liver disease, pulmonary infectious, inflammatory bowel disease and renal failure. Clinically, CEA is used to determine tumor recurrence post-operatively following resection of colon carcinoma.