BioPlex® 2200 ANA Screen with MDSS


The BioPlex™ 2200 ANA Screen with MDSS detects clinically significant antibodies, providing the most relevant information for better diagnosis of systemic autoimmune diseases. Its multiplex technology permits simultaneous detection and identification of many antibodies in a single tube.

The system is intended for the qualitative screening of specific antinuclear antibodies (ANA), the quantitative detection of antibody to dsDNA and the semi-quantitative detection of ten individual antibodies (to chromatin, ribosomal-P protein, SS-A, SS-B, Sm, Sm/RNP, RNP, Scl-70, Jo-1, and centromere B) in human serum and/or EDTA or heparinized plasma. The ANA Screen detects the presence of clinically relevant circulating autoantibodies, which may be useful in diagnosing systemic rheumatoid diseases such as systemic lupus erythematosus (SLE), mixed connective tissue disease (MCTD), undifferentiated connective tissue disease (UCTD), Sjögren's syndrome (SS), scleroderma (systemic sclerosis), dermatomyositis, polymyositis, rheumatoid arthritis (RA), CREST syndrome, and Raynaud's phenomenon.

The BioPlex 2200 Medical Decision Support Software (MDSS), used in conjunction with the ANA Screen, is an optional laboratory tool that associates patient antibody results with predefined MDSS profiles that have been correlated with the following systemic autoimmune diseases: SLE, MCTD, SS, scleroderma, and polymyositis.

The BioPlex 2200 ANA Screen with MDSS is the only autoimmune diagnostic product cleared for use with an interpretive software algorithm.


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BioPlex<sup>®</sup> 2200 ANA Screen Reagent Pack
BioPlex® 2200 ANA Screen Reagent Pack

Reagents for 100 tests for clinically relevant antinuclear autoantibodies on BioPlex® 2200 System; aids in diagnosis of systemic rheumatic diseases

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