Bio-Rad’s assays are suitable for reliable, fast and easy quantitative determination of a broad range of first- and second-generation antiepileptic drugs in plasma and serum. The panel consists of 14 antiepileptics and their active metabolites. Bio-Rad offers an automatable method for measuring more than 10 modern antiepileptics and, in addition, an easy method for determining of levetiracetam. Switching between the tests for Levetiracetam by HPLC and for Antiepileptics by HPLC is easy as the same analytical column is used by both. Bi-level control sets are available.
The manual methods for antiepileptics and levetiracetam feature time-saving, convenient sample preparation with protein precipitation. The fully automated online application for antiepileptics offers high specimen throughput and reduced hands-on time, with an overnight processing option. The analytes can be extracted and separated by online column switching between an extraction cartridge and an analytical column. Now available in packages of 200 tests per kit. With reduced consumption of mobile phase, this assay allows efficient therapeutic drug monitoring in cases of multi-drug treatment.
- Duration of the chromatography: 21 minutes
- Principle: Isocratic HPLC method (Reversed Phase)
- Duration of the chromatography: 16.5 minutes
- Sample volume: 100 µL serum or plasma
- Flow rate: 0.8 mL/min.
- UV Detection: 210 nm