Available kits use affinity chromatography techniques to deplete high-abundance proteins. Enrichment kits use a bead-based library of combinatorial peptide ligands to reduce levels of high-abundance proteins.
ProteoMiner technology. Each bead features a different hexapeptide ligand with affinity for specific proteins in a sample. Samples are applied to the beads, allowing proteins to bind to their specific ligands. Proteins in excess are washed away, and those proteins bound to the beads are eventually eluted, allowing further downstream analysis.
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