Foresight filter plates and columns are prepacked with a range of Bio-Rad process chromatography resins, offering process scientists convenience and reliability for their high-throughput experimentation needs.
Foresight plates are 96-well filter plates prepacked with 20 µl of chromatography media in each well.
Foresight RoboColumn units are offered as single rows of eight prepacked microcolumns. Foresight RoboColumn units are ideal for high-throughput (HT) process development.
Foresight columns are ideal for confirming the operational window obtained through design of experiments (DOE) in trials with Foresight plates and/or Foresight RoboColumn units.
Foresight plates can be used for HT evaluation of various binding, elution, or wash conditions for different chromatography media. They can be processed using manual or automated robotic systems, and sample collection may be achieved through centrifugation or vacuum manifold techniques.
Foresight RoboColumn units are fully compatible with robotic liquid handling systems, allowing process developers to perform automated HT parallel media screening and/or small-scale method development. Multiple rows up to 12 can be combined to form a 96-column array, allowing users to evaluate various chromatography media and conditions in parallel.
Foresight columns may be used for media screening experiments and/or small-scale method development. Foresight columns have standard HPLC connections, which make them compatible with the NGC™ chromatography system and other liquid chromatography systems.
Standard 96-well plate format 128 × 86 × 33 mm
1 × 8 row 128 × 86 × 14 mm
8 × 20 mm (1-ml column) 8 × 100 mm (5-ml column)
59.5-119 (1-ml column) 287.5-595 (5-ml column)
UNOsphere™ Q, UNOsphere S, UNOsphere Rapid S; Nuvia™ Q, Nuvia S, Nuvia™ cPrime™; CHT™ Type I, CHT Type II
Foresight chromatography filter plates and columns are prepacked with a range of Bio-Rad’s process chromatography media, offering process scientists convenience and reliability for their high-throughput (HT) experimentation needs. Their robust design allows process scientists to use the prepacked formats through the entire purification development cycle, from HT media screening to small-scale methods development and scale-up optimization. Learn more
High-throughput experimentation (HTE) was used in this case study in concert with design of experiments (DOE) methodology to study the mass recovery of a basic therapeutic protein (pI 9.2–9.5) using a hydrophobic cation exchange mixed-mode resin.
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