Welcome to the 2-D Doctor™ section on irregular spot patterns. The 2-D Doctor is a self-help guide that enables you to troubleshoot your 2-D gel issues. Here you will find solutions to the problem of irregular spot patterns on 2-D gels.
Other sections in the 2-D Doctor:
Click on the thumbnail that is most representative of your own gel to find out the probable cause of and specific solutions to your problem.
Local Wavy Disturbance of Spots
Missing High Molecular Weight Proteins
Vertically Doubled Spots
Diffuse and Uneven Background in Silver-Stained Gel
Localized Diffuse and Uneven Background in Silver-Stained Gel
For additional help, you can also view videos and browse FAQs.
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